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Mapping genes within a YAC by computer-assisted interpretation of partial restriction digestions.

Partial restriction digestion is used to map restriction sites and the location of genes within yeast artificial chromosomes (YACs). Locus-specific probes are hybridised to the partially digested YAC DNA and the fragments to which they hybridise are compared with the pattern of partial digestion pro...

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Udgivet i:Nucleic Acids Res
Principais autores: Shields, D C, Butler, A, Mosurski, K R, Walsh, M T, Whitehead, A S
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146272/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8948640/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.22.4495
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