CpG island protects Rous sarcoma virus-derived vectors integrated into nonpermissive cells from DNA methylation and transcriptional suppression

CpG islands are important in the protection of adjacent housekeeping genes from de novo DNA methylation and for keeping them in a transcriptionally active state. However, little is known about their capacity to protect heterologous genes and assure position-independent transcription of adjacent tran...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Hejnar, Jir̆í, Hájková, Petra, Plachý, Jir̆í, Elleder, Daniel, Stepanets, Volodymyr, Svoboda, Jan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14627/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11209056/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.98.2.565
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