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CpG island protects Rous sarcoma virus-derived vectors integrated into nonpermissive cells from DNA methylation and transcriptional suppression

CpG islands are important in the protection of adjacent housekeeping genes from de novo DNA methylation and for keeping them in a transcriptionally active state. However, little is known about their capacity to protect heterologous genes and assure position-independent transcription of adjacent tran...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Hejnar, Jir̆í, Hájková, Petra, Plachý, Jir̆í, Elleder, Daniel, Stepanets, Volodymyr, Svoboda, Jan
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14627/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11209056/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.98.2.565
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