CpG island protects Rous sarcoma virus-derived vectors integrated into nonpermissive cells from DNA methylation and transcriptional suppression

CpG islands are important in the protection of adjacent housekeeping genes from de novo DNA methylation and for keeping them in a transcriptionally active state. However, little is known about their capacity to protect heterologous genes and assure position-independent transcription of adjacent tran...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Hejnar, Jir̆í, Hájková, Petra, Plachý, Jir̆í, Elleder, Daniel, Stepanets, Volodymyr, Svoboda, Jan
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 2001
Materias:	Biological Sciences
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14627/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11209056/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.98.2.565
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