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MITF mediates cAMP-induced protein kinase C-β expression in human melanocytes

The cAMP-dependent pathway up-regulates MITF (microphthalmia-associated transcription factor), important for key melanogenic proteins such as tyrosinase, TRP-1 (tyrosinase-related protein 1) and TRP-2. We asked whether MITF is also a key transcription factor for PKC-β (protein kinase C-β), required...

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Detalhes bibliográficos
Main Authors: Park, Hee-Young, Wu, Christina, Yonemoto, Laurie, Murphy-Smith, Melissa, Wu, Heng, Stachur, Christina M., Gilchrest, Barbara A.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462691/
https://ncbi.nlm.nih.gov/pubmed/16411896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051388
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