Role of BMP-4 and Its Signaling Pathways in Cultured Human Melanocytes

Bone Morphogenetic Protein (BMP-4) was shown to down-regulate melanogenesis, in part, by decreasing the level of tyrosinase [Yaar et al. (2006) JBC:281]. Results presented here show that BMP-4 down-regulated the protein levels of TRP-1, PKC-β, and MCI-R. When paired cultures of human melanocytes wer...

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Main Authors: Park, Hee-Young, Wu, Christina, Yaar, Mina, Stachur, Christina M., Kosmadaki, Marita, Gilchrest, Barbara A.
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814237/
https://ncbi.nlm.nih.gov/pubmed/20130821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/750482
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