Using evolutionary rates to investigate protein functional divergence and conservation. A case study of the carbonic anhydrases.

Functional constraints on proteins limit their evolutionary rates at specific sites. These constraints allow for the interpretation of conserved residues and sites with a rate change as those most likely underlying the functional similarities and differences among protein subfamilies, respectively....

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Detaylı Bibliyografya
Asıl Yazarlar: Knudsen, Bjarne, Miyamoto, Michael M, Laipis, Philip J, Silverman, David N
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2003
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462676/
https://ncbi.nlm.nih.gov/pubmed/12930737
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