Properties of intramolecular proton transfer in carbonic anhydrase III.

We investigated the efficiency of glutamic acid 64 and aspartic acid 64 as proton donors to the zinc-bound hydroxide in a series of site-specific mutants of human carbonic anhydrase III (HCA III). Rate constants for this intramolecular proton transfer, a step in the catalyzed dehydration of bicarbon...

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Autores principales: Tu, C, Qian, M, Earnhardt, J N, Laipis, P J, Silverman, D N
Formato: Artigo
Lenguaje:Inglês
Publicado: 1998
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1299658/
https://ncbi.nlm.nih.gov/pubmed/9635771
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