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A likelihood ratio test for evolutionary rate shifts and functional divergence among proteins
Changes in protein function can lead to changes in the selection acting on specific residues. This can often be detected as evolutionary rate changes at the sites in question. A maximum-likelihood method for detecting evolutionary rate shifts at specific protein positions is presented. The method de...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC64713/ https://ncbi.nlm.nih.gov/pubmed/11734650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.251526398 |
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