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Using evolutionary rates to investigate protein functional divergence and conservation. A case study of the carbonic anhydrases.

Functional constraints on proteins limit their evolutionary rates at specific sites. These constraints allow for the interpretation of conserved residues and sites with a rate change as those most likely underlying the functional similarities and differences among protein subfamilies, respectively....

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Sonraí Bibleagrafaíochta
Main Authors: Knudsen, Bjarne, Miyamoto, Michael M, Laipis, Philip J, Silverman, David N
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2003
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462676/
https://ncbi.nlm.nih.gov/pubmed/12930737
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