Regulating general mutation rates: examination of the hypermutable state model for Cairnsian adaptive mutation.

In the lac adaptive mutation system of Cairns, selected mutant colonies but not unselected mutant types appear to arise from a nongrowing population of Escherichia coli. The general mutagenesis suffered by the selected mutants has been interpreted as support for the idea that E. coli possesses an ev...

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Bibliographic Details
Main Authors: Roth, John R, Kofoid, Eric, Roth, Frederick P, Berg, Otto G, Seger, Jon, Andersson, Dan I
Format: Artigo
Language:Inglês
Published: 2003
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462528/
https://ncbi.nlm.nih.gov/pubmed/12702691
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