Evidence that selected amplification of a bacterial lac frameshift allele stimulates Lac(+) reversion (adaptive mutation) with or without general hypermutability.

In the genetic system of Cairns and Foster, a nongrowing population of an E. coli lac frameshift mutant appears to specifically accumulate Lac(+) revertants when starved on medium including lactose (adaptive mutation). This behavior has been attributed to stress-induced general mutagenesis in a subp...

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Autores principales: Slechta, E Susan, Liu, Jing, Andersson, Dan I, Roth, John R
Formato: Artigo
Lenguaje:Inglês
Publicado: 2002
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462195/
https://ncbi.nlm.nih.gov/pubmed/12136002
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