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Changing effective population size and the McDonald-Kreitman test.
Artifactual evidence of adaptive amino acid substitution can be generated within a McDonald-Kreitman test if some amino acid mutations are slightly deleterious and there has been an increase in effective population size. Here I investigate the conditions under which this occurs. I show that fairly s...
Αποθηκεύτηκε σε:
Κύριος συγγραφέας: | |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
2002
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1462352/ https://ncbi.nlm.nih.gov/pubmed/12524367 |
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