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SIR2-induced inviability is suppressed by histone H4 overexpression.

We have identified histone H4 as a high-expression suppressor of Sir2-induced inviability in yeast cells. Overexpression of histone H3 does not suppress Sir2-induced lethality, nor does overexpression of histone H4 alleles associated with silencing defects. These results suggest a direct and specifi...

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Hlavní autoři: Matecic, Mirela, Stuart, Shelagh, Holmes, Scott G
Médium: Artigo
Jazyk:Inglês
Vydáno: 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462276/
https://ncbi.nlm.nih.gov/pubmed/12399404
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