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New Alleles of SIR2 Define Cell-Cycle-Specific Silencing Functions

The establishment of transcriptional silencing in yeast requires cell-cycle progression, but the nature of this requirement is unknown. Sir2 is a protein deacetylase that is required for gene silencing in yeast. We have used temperature-sensitive alleles of the SIR2 gene to assess Sir2's contri...

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Detalhes bibliográficos
Main Authors: Matecic, Mirela, Martins-Taylor, Kristen, Hickman, Merrit, Tanny, Jason, Moazed, Danesh, Holmes, Scott G.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright © 2006 by the Genetics Society of America 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569706/
https://ncbi.nlm.nih.gov/pubmed/16783021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.055491
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