Steps in Assembly of Silent Chromatin in Yeast: Sir3-Independent Binding of a Sir2/Sir4 Complex to Silencers and Role for Sir2-Dependent Deacetylation

Transcriptional silencing at the budding yeast silent mating type (HM) loci and telomeric DNA regions requires Sir2, a conserved NAD-dependent histone deacetylase, Sir3, Sir4, histones H3 and H4, and several DNA-binding proteins. Silencing at the yeast ribosomal DNA (rDNA) repeats requires a complex...

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Detalhes bibliográficos
Main Authors: Hoppe, Georg J., Tanny, Jason C., Rudner, Adam D., Gerber, Scott A., Danaie, Sherwin, Gygi, Steven P., Moazed, Danesh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133845/
https://ncbi.nlm.nih.gov/pubmed/12024030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.12.4167-4180.2002
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