Triplex-forming oligonucleotides trigger conformation changes of a target hairpin sequence.

We used a DNA duplex formed between the 5' end of a 69mer (69T) and an 11mer (OL7) as a substrate for BamHI. The former oligonucleotide folds into a hairpin structure, the stem of which contains a stretch of pyrimidines in one strand and consequently a stretch of purines in the other strand. Th...

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Bibliographic Details
Main Authors: Brossalina, E, Demchenko, E, Demchenko, Y, Vlassov, V, Toulmé, J J
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC146096/
https://ncbi.nlm.nih.gov/pubmed/8811094
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