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The Remarkable Transport Mechanism of P-glycoprotein; a Multidrug Transporter
Human P-glycoprotein (ABCB1) is a primary multidrug transporter located in plasma membranes, that, utilizes the energy of ATP hydrolysis to pump toxic xenobiotics out of cells. P-glycoprotein employs a most unusual molecular mechanism to perform this drug transport function. Here we review our work...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1459968/ https://ncbi.nlm.nih.gov/pubmed/16691488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10863-005-9497-5 |
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