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Cortisol is transported by the multidrug resistance gene product P-glycoprotein.

The physiology of the multidrug transporter P-glycoprotein (Pgp) is still poorly understood. We now show evidence that cell lines with a high expression of Pgp display a reduced accumulation of cortisol and an ATP-dependent outward transport of the hormone. Cortisol efflux from Pgp negative cells do...

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Autors principals: van Kalken, C. K., Broxterman, H. J., Pinedo, H. M., Feller, N., Dekker, H., Lankelma, J., Giaccone, G.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1993
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968171/
https://ncbi.nlm.nih.gov/pubmed/8094292
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