Functional detection of MDR1/P170 and MRP/P190-mediated multidrug resistance in tumour cells by flow cytometry.

Multidrug resistance (MDR) in tumour cells is often caused by the overexpression of the plasma membrane drug transporter P-glycoprotein (P-gp) or the recently discovered multidrug resistance-associated protein (MRP). In this study we investigated the specificity and sensitivity of the fluorescent pr...

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Bibliografiske detaljer
Main Authors: Feller, N., Kuiper, C. M., Lankelma, J., Ruhdal, J. K., Scheper, R. J., Pinedo, H. M., Broxterman, H. J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033905/
https://ncbi.nlm.nih.gov/pubmed/7669559
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