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Expression of 5-lipoxygenase and leukotriene A(4) hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability
Leukotrienes (LT) are a group of proinflammatory lipid mediators that are implicated in the pathogenesis and progression of atherosclerosis. Here we report that mRNA levels for the three key proteins in LTB(4) biosynthesis, namely 5-lipoxygenase (5-LO), 5-LO-activating protein (FLAP), and LTA(4) hyd...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1459628/ https://ncbi.nlm.nih.gov/pubmed/16698924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602414103 |
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