IPRO: An Iterative Computational Protein Library Redesign and Optimization Procedure

A number of computational approaches have been developed to reengineer promising chimeric proteins one at a time through targeted point mutations. In this article, we introduce the computational procedure IPRO (iterative protein redesign and optimization procedure) for the redesign of an entire comb...

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Bibliografiske detaljer
Main Authors: Saraf, Manish C., Moore, Gregory L., Goodey, Nina M., Cao, Vania Y., Benkovic, Stephen J., Maranas, Costas D.
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2006
Fag:
Proteins
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459523/
https://ncbi.nlm.nih.gov/pubmed/16513775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.079277
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