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OptStrain: A computational framework for redesign of microbial production systems

This paper introduces the hierarchical computational framework OptStrain aimed at guiding pathway modifications, through reaction additions and deletions, of microbial networks for the overproduction of targeted compounds. These compounds may range from electrons or hydrogen in biofuel cell and envi...

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Detalhes bibliográficos
Main Authors: Pharkya, Priti, Burgard, Anthony P., Maranas, Costas D.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC525696/
https://ncbi.nlm.nih.gov/pubmed/15520298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.2872004
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