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OptStrain: A computational framework for redesign of microbial production systems

This paper introduces the hierarchical computational framework OptStrain aimed at guiding pathway modifications, through reaction additions and deletions, of microbial networks for the overproduction of targeted compounds. These compounds may range from electrons or hydrogen in biofuel cell and envi...

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Autori principali: Pharkya, Priti, Burgard, Anthony P., Maranas, Costas D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC525696/
https://ncbi.nlm.nih.gov/pubmed/15520298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.2872004
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