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Physically realistic homology models built with rosetta can be more accurate than their templates
We have developed a method that combines the rosetta de novo protein folding and refinement protocol with distance constraints derived from homologous structures to build homology models that are frequently more accurate than their templates. We test this method by building complete-chain models for...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1459360/ https://ncbi.nlm.nih.gov/pubmed/16567638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509355103 |
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