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Homology modeling using parametric alignment ensemble generation with consensus and energy-based model selection

The accuracy of a homology model based on the structure of a distant relative or other topologically equivalent protein is primarily limited by the quality of the alignment. Here we describe a systematic approach for sequence-to-structure alignment, called ‘K*Sync’, in which alignments are generated...

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Bibliografski detalji
Glavni autori: Chivian, Dylan, Baker, David
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635247/
https://ncbi.nlm.nih.gov/pubmed/16971460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl480
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