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A Dirichlet process model for detecting positive selection in protein-coding DNA sequences

Most methods for detecting Darwinian natural selection at the molecular level rely on estimating the rates or numbers of nonsynonymous and synonymous changes in an alignment of protein-coding DNA sequences. In some of these methods, the nonsynonymous rate of substitution is allowed to vary across th...

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Autors principals: Huelsenbeck, John P., Jain, Sonia, Frost, Simon W. D., Pond, Sergei L. Kosakovsky
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458866/
https://ncbi.nlm.nih.gov/pubmed/16606848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508279103
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