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A Dirichlet process model for detecting positive selection in protein-coding DNA sequences

Most methods for detecting Darwinian natural selection at the molecular level rely on estimating the rates or numbers of nonsynonymous and synonymous changes in an alignment of protein-coding DNA sequences. In some of these methods, the nonsynonymous rate of substitution is allowed to vary across th...

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書目詳細資料
Main Authors: Huelsenbeck, John P., Jain, Sonia, Frost, Simon W. D., Pond, Sergei L. Kosakovsky
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458866/
https://ncbi.nlm.nih.gov/pubmed/16606848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508279103
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