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A counting renaissance: combining stochastic mapping and empirical Bayes to quickly detect amino acid sites under positive selection
Motivation: Statistical methods for comparing relative rates of synonymous and non-synonymous substitutions maintain a central role in detecting positive selection. To identify selection, researchers often estimate the ratio of these relative rates ([Image: see text]) at individual alignment sites....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3579240/ https://ncbi.nlm.nih.gov/pubmed/23064000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts580 |
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