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Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis

The RD1 genomic region is present in virulent strains of Mycobacterium tuberculosis (MTB), missing from the vaccine strain M. bovis BCG, and its importance to virulence has been established experimentally. Based on in silico analysis, it has been suggested that RD1 may encode a novel secretion syste...

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Bibliografiset tiedot
Päätekijät: Guinn, Kristi M., Hickey, Mark J., Mathur, Sanjeev K., Zakel, Kelly L., Grotzke, Jeff E., Lewinsohn, David M., Smith, Sherilyn, Sherman, David R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458497/
https://ncbi.nlm.nih.gov/pubmed/14756778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2958.2003.03844.x
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