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Macrophage Immune Response Suppression by Recombinant Mycobacterium tuberculosis Antigens, the ESAT-6, CFP-10, and ESAT-6/CFP-10 Fusion Proteins

BACKGROUND: Macrophage immune responses are affected by the secretory proteins of Mycobacterium tuberculosis (Mtb). This study aimed to examine the immune responses of macrophages to Mtb secretory antigens, namely ESAT-6, CFP-10, and ESAT-6/CFP-10. METHODS: THP-1 cells (a human monocytic cell line)...

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Bibliographic Details
Published in:Iran J Med Sci
Main Authors: Seghatoleslam, Atefeh, Hemmati, Mina, Ebadat, Saeedeh, Movahedi, Bahram, Mostafavi-Pour, Zohreh
Format: Artigo
Language:Inglês
Published: Iranian Journal of Medical Sciences 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912648/
https://ncbi.nlm.nih.gov/pubmed/27365551
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