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Macrophage Immune Response Suppression by Recombinant Mycobacterium tuberculosis Antigens, the ESAT-6, CFP-10, and ESAT-6/CFP-10 Fusion Proteins

BACKGROUND: Macrophage immune responses are affected by the secretory proteins of Mycobacterium tuberculosis (Mtb). This study aimed to examine the immune responses of macrophages to Mtb secretory antigens, namely ESAT-6, CFP-10, and ESAT-6/CFP-10. METHODS: THP-1 cells (a human monocytic cell line)...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Iran J Med Sci
Prif Awduron: Seghatoleslam, Atefeh, Hemmati, Mina, Ebadat, Saeedeh, Movahedi, Bahram, Mostafavi-Pour, Zohreh
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Iranian Journal of Medical Sciences 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912648/
https://ncbi.nlm.nih.gov/pubmed/27365551
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