Macrophage Immune Response Suppression by Recombinant Mycobacterium tuberculosis Antigens, the ESAT-6, CFP-10, and ESAT-6/CFP-10 Fusion Proteins

BACKGROUND: Macrophage immune responses are affected by the secretory proteins of Mycobacterium tuberculosis (Mtb). This study aimed to examine the immune responses of macrophages to Mtb secretory antigens, namely ESAT-6, CFP-10, and ESAT-6/CFP-10. METHODS: THP-1 cells (a human monocytic cell line)...

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Publicado en:Iran J Med Sci
Autores principales: Seghatoleslam, Atefeh, Hemmati, Mina, Ebadat, Saeedeh, Movahedi, Bahram, Mostafavi-Pour, Zohreh
Formato: Artigo
Lenguaje:Inglês
Publicado: Iranian Journal of Medical Sciences 2016
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912648/
https://ncbi.nlm.nih.gov/pubmed/27365551
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