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Mycobacterium tuberculosis H37Rv:ΔRD1 Is More Virulent than M. bovis Bacille Calmette-Guérin in Long-Term Murine Infection
Region of difference (RD1) genes are present in virulent Mycobacterium tuberculosis but not the vaccine strain M. bovis bacille Calmette-Guérin (BCG). The deletion of RD1 from M. tuberculosis produces an attenuation strikingly like that of BCG, which suggests the use of RD1 mutant strains for improv...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1458499/ https://ncbi.nlm.nih.gov/pubmed/15195251 |
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