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Structure and function of the complex formed by the tuberculosis virulence factors CFP-10 and ESAT-6
The secreted Mycobacterium tuberculosis complex proteins CFP-10 and ESAT-6 have recently been shown to play an essential role in tuberculosis pathogenesis. We have determined the solution structure of the tight, 1:1 complex formed by CFP-10 and ESAT-6, and employed fluorescence microscopy to demonst...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1176459/ https://ncbi.nlm.nih.gov/pubmed/15973432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600732 |
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