Structure and function of the complex formed by the tuberculosis virulence factors CFP-10 and ESAT-6

The secreted Mycobacterium tuberculosis complex proteins CFP-10 and ESAT-6 have recently been shown to play an essential role in tuberculosis pathogenesis. We have determined the solution structure of the tight, 1:1 complex formed by CFP-10 and ESAT-6, and employed fluorescence microscopy to demonst...

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Autori principali: Renshaw, Philip S, Lightbody, Kirsty L, Veverka, Vaclav, Muskett, Fred W, Kelly, Geoff, Frenkiel, Thomas A, Gordon, Stephen V, Hewinson, R Glyn, Burke, Bernard, Norman, Jim, Williamson, Richard A, Carr, Mark D
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2005
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1176459/
https://ncbi.nlm.nih.gov/pubmed/15973432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600732
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