Oligonucleotide N3'-->P5' phosphoramidates as antisense agents.
Uniformly modified oligonucleotide N3'-->P5' phosphoramidates, where every 3'-oxygen is replaced by a 3'-amino group, were synthesized. These compounds have very high affinity to single-stranded RNAs and thus have potential utility as antisense agents. As was shown in this study, the oligonucleotide...
Zapisane w:
| Wydane w: | Nucleic Acids Res |
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| Główni autorzy: | , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
1996
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145826/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8628685/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.8.1508 |
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