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Age-dependent silencing of globin transgenes in the mouse.

Variegation of transgene expression, a heterocellular or mosaic pattern of expression seen in all mice in a given transgenic line, is a frequently observed but unexplained phenomenon. We have encountered variegation with globin transgenes; when lacZ expression is driven by globin control elements a...

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Autors principals: Robertson, G, Garrick, D, Wilson, M, Martin, D I, Whitelaw, E
Format: Artigo
Idioma:Inglês
Publicat: 1996
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC145804/
https://ncbi.nlm.nih.gov/pubmed/8628679
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