NMR investigations of duplex stability of phosphorothioate and phosphorodithioate DNA analogues modified in both strands.
Duplex formation from the self-complementary 12mer d(CGCGAATTCGCG) (Dickerson dodecamer) in which all phosphodiester linkages were replaced by phosphorothioate or phosphorodithioate linkages was studied using variable-temperature 1H and 31P NMR spectroscopy. Melting temperatures of the dodecamer, me...
محفوظ في:
| الحاوية / القاعدة: | Nucleic Acids Res |
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| المؤلفون الرئيسيون: | , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Oxford University Press
1996
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145729/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8600448/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.5.829 |
| الوسوم: |
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