Construction and selection of bead-bound combinatorial oligonucleoside phosphorothioate and phosphorodithioate aptamer libraries designed for rapid PCR-based sequencing

Chemically synthesized combinatorial libraries of unmodified or modified nucleic acids have not previously been used in methods to rapidly select oligonucleotides binding to target biomolecules such as proteins. Phosphorothioate oligonucleotides (S-ODNs) or phosphorodithioate oligonucleotides (S(2)-...

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Detalhes bibliográficos
Main Authors: Yang, Xianbin, Bassett, Suzanne E., Li, Xin, Luxon, Bruce A., Herzog, Norbert K., Shope, Robert E., Aronson, Judy, Prow, Tarl W., Leary, James F., Kirby, Romy, Ellington, Andrew D., Gorenstein, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
NAR Methods Online
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC137987/
https://ncbi.nlm.nih.gov/pubmed/12466564
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