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Construction and selection of bead-bound combinatorial oligonucleoside phosphorothioate and phosphorodithioate aptamer libraries designed for rapid PCR-based sequencing

Chemically synthesized combinatorial libraries of unmodified or modified nucleic acids have not previously been used in methods to rapidly select oligonucleotides binding to target biomolecules such as proteins. Phosphorothioate oligonucleotides (S-ODNs) or phosphorodithioate oligonucleotides (S(2)-...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Yang, Xianbin, Bassett, Suzanne E., Li, Xin, Luxon, Bruce A., Herzog, Norbert K., Shope, Robert E., Aronson, Judy, Prow, Tarl W., Leary, James F., Kirby, Romy, Ellington, Andrew D., Gorenstein, David G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137987/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12466564/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gnf132
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