TRPM2 activation by cyclic ADP-ribose at body temperature is involved in insulin secretion

There are eight thermosensitive TRP (transient receptor potential) channels in mammals, and there might be other TRP channels sensitive to temperature stimuli. Here, we demonstrate that TRPM2 can be activated by exposure to warm temperatures (>35°C) apparently via direct heat-evoked channel gatin...

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Hlavní autoři: Togashi, Kazuya, Hara, Yuji, Tominaga, Tomoko, Higashi, Tomohiro, Konishi, Yasunobu, Mori, Yasuo, Tominaga, Makoto
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456947/
https://ncbi.nlm.nih.gov/pubmed/16601673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601083
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