Cyclic ADP-Ribose and Heat Regulate Oxytocin Release via CD38 and TRPM2 in the Hypothalamus during Social or Psychological Stress in Mice

Hypothalamic oxytocin (OT) is released into the brain by cyclic ADP-ribose (cADPR) with or without depolarizing stimulation. Previously, we showed that the intracellular free calcium concentration ([Ca(2+)](i)) that seems to trigger OT release can be elevated by β-NAD(+), cADPR, and ADP in mouse oxy...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Zhong, Jing, Amina, Sarwat, Liang, Mingkun, Akther, Shirin, Yuhi, Teruko, Nishimura, Tomoko, Tsuji, Chiharu, Tsuji, Takahiro, Liu, Hong-Xiang, Hashii, Minako, Furuhara, Kazumi, Yokoyama, Shigeru, Yamamoto, Yasuhiko, Okamoto, Hiroshi, Zhao, Yong Juan, Lee, Hon Cheung, Tominaga, Makoto, Lopatina, Olga, Higashida, Haruhiro
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956647/
https://ncbi.nlm.nih.gov/pubmed/27499729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00304
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