Cyclic ADP-Ribose and Heat Regulate Oxytocin Release via CD38 and TRPM2 in the Hypothalamus during Social or Psychological Stress in Mice

Hypothalamic oxytocin (OT) is released into the brain by cyclic ADP-ribose (cADPR) with or without depolarizing stimulation. Previously, we showed that the intracellular free calcium concentration ([Ca(2+)](i)) that seems to trigger OT release can be elevated by β-NAD(+), cADPR, and ADP in mouse oxy...

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Détails bibliographiques
Publié dans:Front Neurosci
Auteurs principaux: Zhong, Jing, Amina, Sarwat, Liang, Mingkun, Akther, Shirin, Yuhi, Teruko, Nishimura, Tomoko, Tsuji, Chiharu, Tsuji, Takahiro, Liu, Hong-Xiang, Hashii, Minako, Furuhara, Kazumi, Yokoyama, Shigeru, Yamamoto, Yasuhiko, Okamoto, Hiroshi, Zhao, Yong Juan, Lee, Hon Cheung, Tominaga, Makoto, Lopatina, Olga, Higashida, Haruhiro
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2016
Sujets:
Endocrinology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956647/
https://ncbi.nlm.nih.gov/pubmed/27499729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00304
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