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An aging pathway controls the TrkA to p75(NTR) receptor switch and amyloid β-peptide generation

Aging of the brain is characterized by marked changes in the expression levels of the neurotrophin receptors, TrkA and p75(NTR). An expression pattern in which TrkA predominates in younger animals switches to one in which p75(NTR) predominates in older animals. This TrkA-to-p75(NTR) switch is accomp...

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Detalhes bibliográficos
Main Authors: Costantini, Claudio, Scrable, Heidi, Puglielli, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456930/
https://ncbi.nlm.nih.gov/pubmed/16619032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601062
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