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Inhibition of apoptosis by survivin improves transplantation of pancreatic islets for treatment of diabetes in mice
Survivin is a cancer gene implicated in inhibition of apoptosis and regulation of mitosis, but its function in normal cells has remained elusive. Here, we show that transgenic mice expressing survivin in pancreatic islet β-cells show no changes in cell proliferation, as determined by islet size or i...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2006
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1456913/ https://ncbi.nlm.nih.gov/pubmed/16470228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400640 |
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