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Essential Role of the Small GTPase Ran in Postnatal Pancreatic Islet Development
The small GTPase Ran orchestrates pleiotropic cellular responses of nucleo-cytoplasmic shuttling, mitosis and subcellular trafficking, but whether deregulation of these pathways contributes to disease pathogenesis has remained elusive. Here, we generated transgenic mice expressing wild type (WT) Ran...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3219697/ https://ncbi.nlm.nih.gov/pubmed/22114719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027879 |
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