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COMPARTMENTALIZED PHOSPHORYLATION OF IAP BY PROTEIN KINASE A REGULATES CYTOPROTECTION
Cell death pathways are likely regulated in specialized subcellular microdomains, but how this occurs is not understood. Here, we show that cyclic AMP-dependent protein kinase A (PKA) phosphorylates the Inhibitor of Apoptosis (IAP) protein survivin on Ser20 in the cytosol, but not in mitochondria. T...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1986705/ https://ncbi.nlm.nih.gov/pubmed/17612487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.06.004 |
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