Smg1 Nonsense Mutations Do Not Abolish Nonsense-Mediated mRNA Decay in Drosophila melanogaster

Smg1 is a key component of nonsense-mediated decay (NMD) in Caenorhabditis elegans and mammals. Here we report that two nonsense alleles of the ortholog of Smg1 do not affect NMD in Drosophila melanogaster.

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Bibliographic Details
Main Authors: Chen, Zhenzhong, Smith, Katherine R., Batterham, Philip, Robin, Charles
Format: Artigo
Language:Inglês
Published: Copyright © 2005 by the Genetics Society of America 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456532/
https://ncbi.nlm.nih.gov/pubmed/15965240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.045674
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