Unwinding of the third strand of a DNA triple helix, a novel activity of the SV40 large T-antigen helicase.
We present experiments indicating that the SV40 large T-antigen (T-ag) helicase is capable of unwinding the third strand of DNA triple helices. Intermolecular d(TC)(20)d(GA)(20)d(TC)(20) triplexes were generated by annealing, at pH 5.5, a linearized double-stranded plasmid containing a d(TC)(27).d(G...
Enregistré dans:
| Publié dans: | Nucleic Acids Res |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
1996
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145642/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8628658/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.2.330 |
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