Backbone and benzoyl mustard carrying moiety modifies DNA interactions of distamycin analogues.
Alkylating distamycin derivative FCE-24517 (l) is the prototype of a novel class of alkylating agents. In the present study we have investigated the effect of further chemical modifications introduced in the alkylating distamycin-derived molecule with the aim of improving their ability to bind DNA....
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| Publicado en: | Nucleic Acids Res |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
1996
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145640/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8628655/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.2.311 |
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