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Backbone and benzoyl mustard carrying moiety modifies DNA interactions of distamycin analogues.

Alkylating distamycin derivative FCE-24517 (l) is the prototype of a novel class of alkylating agents. In the present study we have investigated the effect of further chemical modifications introduced in the alkylating distamycin-derived molecule with the aim of improving their ability to bind DNA....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Ciucci, A, Manzini, S, Lombardi, P, Arcamone, F
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 1996
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145640/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8628655/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.2.311
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