Backbone and benzoyl mustard carrying moiety modifies DNA interactions of distamycin analogues.

Alkylating distamycin derivative FCE-24517 (l) is the prototype of a novel class of alkylating agents. In the present study we have investigated the effect of further chemical modifications introduced in the alkylating distamycin-derived molecule with the aim of improving their ability to bind DNA....

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Ciucci, A, Manzini, S, Lombardi, P, Arcamone, F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145640/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8628655/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.2.311
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